From Little Things, Big Things Grow: NBMLHD Research Showcase 2025

This year’s theme, From Little Things, Big Things Grow, demonstrated how small ideas can lead to significant changes in practice.

The first day, led in Partnership with Sydney Health Partners, focused on translating evidence into real-world clinical settings. ICU physician and NBMLHD Board Member, Dr Nhi Nguyen, delivered the keynote address, sharing insights from a project she is leading to reduce wasteful and unnecessary testing in the ICU setting. Local clinicians and researchers presented projects demonstrating creative approaches to implementing evidence into practice.

The second day brought together research and clinician thought leaders to share projects that have a tangible impact on patient care, from improving management for patients with chronic and complex conditions, like obesity and diabetes, to using AI and technology to enhance treatment and care.

Pictured: Prof Louise Baur, Douglas Burrows Professor of Paediatrics & Child Health, The University of Sydney. 

Dietary Supplement Could Enhance Peanut Allergy Treatment
Dr Gabriela Pinget presented findings from a study co-led with Dr Duan Ni and supervised by Professor Ralph Nanan on the use of butyrylated high-amylose maize starch (HAMSB) to support peanut oral immunotherapy in food allergy children. The supplement increased protective metabolites and immune-regulating cells, offering the first evidence that dietary supplementation could modulate the immune system and potentially improve allergy treatment outcomes.

Isotretinoin Exposure in Pregnancy Remains a Risk
Laura Gerhardy shared population-level research on pregnancy outcomes in women exposed to a highly effective acne drug known to cause birth defects. Data from 2003–2020 revealed 596 exposed pregnancies in NSW, with 80% ending in miscarriage or termination. The study underscores the ongoing need for stronger contraceptive guidance and patient counselling.

New Program Supports Families Affected by Hoarding Disorder
Emily Dewar discussed the development of a six-week cognitive behavioural program for families of people with hoarding disorder. Drawing on interviews with families and their relatives affected by hoarding, and informed input from international experts, and clinicians, this evidence-based group program provides practical skills, coping strategies, and an individual coaching session to help address complex challenges families face. Early evaluations indicate strong acceptability and feasibility, with improved outcomes for participating family members.

Understanding Use of Child & Family Health Nursing Services
Kylie Davis explored why parents engage with Child and Family Health Nursing services. A survey of 459 parents revealed that while most valued the services, only 39% attended regularly. Convenience, continuity of care, staff skills, and cultural sensitivity were key factors influencing engagement. The findings highlight opportunities to improve access and promote these essential public services.

Recognising Research Excellence
The Showcase also celebrated outstanding contributions:

• Best Student Oral Presentation – Ellen Small

• Best Student Poster – Hunter McAuliffe, The University of Sydney

• Best Early-Mid Career Researcher Oral Presentation – Dr Maria Lastra Cagigas
• Best Early-Mid Career Researcher Poster – Dr Emily Dewar, Western Sydney University
• Best Clinician Researcher Oral Presentation – Jason Lam
• Best Clinician Researcher Poster – Kristy Stoten & Nicola Drayton

Dr Kelly Thompson, NBMLHD Director of Research Operations, said:

"From little things, big things grow is a wonderful opportunity to showcase the incredible talent, depth and diversity of research happening across NBMLHD. There is a clear focus on improving outcomes and service delivery. It’s so important to provide a space to learn and celebrate the amazing clinicians and researchers who are working tirelessly, and often in their own time, generate evidence that solves real-world health and system challenges”.

By partnering with the University of Sydney, Sydney Health Partners, Western Sydney University, and The University of Notre Dame, NBMLHD continues to turn small research ideas into innovations that transform healthcare delivery and improve patient outcomes.