About our Dermatology Research Centre
The Department of Dermatology provides clinical, surgical, research and education services in skin health.
We are part of the Sydney Medical School at The University of Sydney, and the Research and Education Network at Westmead Hospital, Western Sydney Local Health District (LHD).
We collaborate and work closely with:
Our services
We offer general dermatology and specialist clinics for a wide range of skin conditions, including:
- psoriasis
- eczema
- autoimmune diseases
- lupus
- scleroderma
- porphyria
- bullous diseases.
Our main area of focus is oncodermatology — the diagnosis and treatment of skin cancers.
Specialist clinics in oncodermatology
We run dedicated clinics for:
- transplant patients, including solid organ and bone marrow transplant recipients
- melanoma
- high-risk melanoma
- cutaneous lymphoma.
We work in partnership with The Skin Hospital (Skin and Cancer Foundation Australia) to operate a tissue bank for non-melanoma skin cancer.
Clinical research
For more information about our clinical trials email: wm.derm.ct@sydney.edu.au
Our current clinical trials include:
- A Phase 3 Multicentre Study of the Safety and Efficacy of Adalimumab in Subjects with Moderate to Severe Hidradenitis-Suppurativa.
- A 28-Week, Phase 3, Randomized, Active Comparator and Placebo-Controlled, Parallel Design Study to Evaluate the Efficacy and Safety/Tolerability of Subcutaneous SCH 900222 / MK-3222, followed by an Optional Long-Term Safety Extension Study, in Subjects With Moderate-to-Severe Chronic Plaque Psoriasis.
- A randomised controlled multicentre trial of imiquimod versus radiotherapy for lentigo maligna (LM) when staged surgical excision with 5mm margins is not possible, is refused, or fails.
- Open-Label, Multi-Center, Randomized Study of Anti-CCR4 Monoclonal Antibody KW-0761 (mogamulizumab) Versus Vorinostat in Subjects with Previously Treated Cutaneous T-Cell Lymphoma. A multicentre observation of a cohort who are at high risk for the development of primary melanoma of the skin.
- A Phase 3, Multicentre, Randomized, Double-blind, Placebo and Active Comparator-controlled Study Evaluating the Efficacy and Safety of Guselkumab for the Treatment of Subjects with Moderate to Severe Plaque-type Psoriasis with Randomized Withdrawal and Retreatment (VOYAGE 2).
Translational Research Projects
Translational research projects are studies that turn laboratory findings into practical treatments or care.
Our current projects include:
- Proteomic analysis of formalin-fixed, paraffin-embedded non-melanoma skin cancers.
- Depth of action of PUVA and narrow band-UVB in cutaneous T cell lymphomas.
- Anti-Programmed Death 1(Anti-PD1): Cutaneous manifestations and the mechanisms leading to cutaneous adverse events in patients with malignancy.
- The clinical course of Cimicosis; the dermatological affects from the bite of the common bed bug, Cimex lectularius.
- The molecular interplay involved in the formation of cutaneous lesions seen in patients taking BRAFi.
- Mechanisms in Grover’s disease.
- Pathways in the development of UV induced SCC and keratoacanthomas in patients.
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