About the Department of Respiratory and Sleep Medicine Research
The Department is a leading education and research centre for resident staff, students, physicians and general practitioners.
We are recognised locally and internationally for producing high-quality original research. Our key research areas include:
- upper airway physiology
- mechanics of chest wall muscles
- cystic fibrosis.
Our clinical trials unit tests new medicines to help improve health outcomes for people with respiratory and sleep conditions.
Director: Professor John Wheatly.
Our clinical trials
We run clinical trials in these areas:
- asthma
- Chronic Obstructive Pulmonary Disease (COPD)
- bronchiectasis
- cystic fibrosis
- sleep apnoea
- insomnia
- Pulmonary Arterial Hypertension
- Idiopathic Pulmonary Fibrosis (IPF).
We welcome people who are interested in joining clinical trials. The trials now open for recruitment are:
Asthma study
NAVIGATOR – A multicentre, placebo controlled, phase 3 study to evaluate the efficacy and safety of Tezepelumab in adults with severe uncontrolled asthma.
This is a 12-month placebo-controlled study with monthly visits to the clinic. All travel and parking expenses will be compensated for.
Pulmonary Arterial Hypertension (PAH)
PULSAR – A multicentre, placebo controlled, phase 2 study to compare the efficacy and safety of Sotatercept when added to standard of care for the treatment of PAH.
This study is a 24-week placebo-controlled study with visits to the clinic every 3 weeks. Participants who complete the 24-week study will be eligible to continue into the 18-month extension period to receive open label study drug.
All travel and parking expenses will be compensated for.
Non-CF Bronchiectasis
PROMIS 1 – A multicentre, placebo controlled, phase 3 study to investigate the efficacy and safety of inhaled colistemethate sodium in the treatment of participants with non-cystic fibrosis bronchiectasis chronically infected with Pseudomonas aeruginosa.
This is a 12-month placebo-controlled study with visits to the clinic once every 3 months.
All travel and parking expenses will be compensated for.
Contact us
For information about clinical trial participation contact:
Tracey Burns - Clinical Research Manager
Email: Tracey.burns@health.nsw.gov.au
Phone: (02) 8890 7785